It is quite common among people who experience pain to order Tapentadol IR online. What does instant release mean? Is there any precaution to handle before using Tapentadol instant-release pills?




The pill contains the active ingredient covered with a small film coating. The film coating helps the tablet to withstand environmental factors, especially moisture. The film can dissolve inside the body, very fast. Once the pill is inside the body, the film dissolves, allowing the active ingredient to mix into the system.


In the conventional (instant-release) pill, the active ingredient’s absorption rate depends on intestinal metabolism, chemical hydrolysis, and others. When you order Tapentadol IR online, remember that the on-set time (time taken for the medicine to take action) varies with metabolism rate, age, the health of organs, and other underlying medical conditions.

On-set time

According to a study, it takes a minimum of 30 minutes to release 85% of the active ingredient into the system. It is imperative to know the on-set time when you order Tapentadol IR online. The minimum on-set time is 30 minutes. However, it could take up to one hour to create an effect. It is essential to wait for the medicine to act, instead of popping the second pill. Even if you are not able to feel relief after one hour, it is best not to double the dose (unless recommended by your doctor). There should be at least four to six hours between two doses, and in a day, you should not take more than 600mg.

What should you do if you are not able to feel relief after taking the pill? There are two reasons for such a situation.

  1. Prolonged use
  2. Ineffective dose

Prolonged use

You should buy Tapentadol COD online only for short use. If you use the pill for a longer duration, your body might get tolerant to the medicine. You would not feel relief even after consuming the right dose. According to a study, the chances of tolerance development are quite low in Tapentadol, compared to similar opioid pills. However, if you are using Tapentadol instant-release for a very long time, the lack of pain relief could be due to prolonged use.


Ineffective dose

The right dose for an individual varies with several factors. Some of the prominent factors are age, gender, underlying medical condition, the severity of the pain, and so on. Doctors take these factors into account while specifying a dose. However, there are some indirect factors like metabolism, liver function, and so on. Thus, the dosage recommended by the doctor might be insufficient.


In either case, do not order more TapenTadol instant release cash on delivery packages and consume more pills. Talk to your doctor and get a prescription for a new dose or treatment method.


In general, when you buy TapenTadol 100mg cash on delivery, the recommended dose is 50-100mg. The recommended time gap between two doses is 6 hours (maximum of 4 hours). In the case of extreme pain, the gap between the very first and second dose can be one hour. The rest of the doses should be at an interval of 4-6 hours. On the first day, the maximum dose is 700mg per day, and for the rest of the days, the maximum recommended dose is 600mg per day.


Respiratory distress is quite common during the first 72 hours. Thus, it is essential to have strict monitoring.


For chronic pain

If you are experiencing chronic pain, it is best to buy the extended-release version of the pill. Buy immediate-release Tapentadol USA to USA delivery only for mild to moderate acute pain.


For patients with liver dysfunction

Those with serious medical problems in the liver should not buy Tapentadol without prescription. If you have mild liver dysfunction, the dose is 50mg per every 8 hours. This medicine is not for those with severe liver problems.


For senior citizens

Unless there is a renal dysfunction involved, the usual dose is enough. In the case of renal dysfunction, the doctor would recommend a dose based on kidney health.


Overdose and missed dose

If you missed a dose, take it when you remember it. Alter the next dose so that it is 4 to 6 hours away from it. If overdosed, it is imperative to get medical help. Overdose might lead to coma, seizure, shallow breathing, slow heartbeat, and others. Even if there are no overdose symptoms, it is best to seek medical help if overdosed.

What not to do while under Tapentadol IR?

Even if you are healthy enough to take Tapentadol IR without any dose change, adverse effects are possible due to drug interaction. While you are under this drug, it is best to take the necessary precautions.

  • Tapentadol is an opioid drug, which has a high probability of causing dependency or habit formation. Those who have a substance abuse history should make sure to give the pill control to someone closer.
  • Those who have any respiratory problems should not consume Tapentadol IR without the doctor’s approval.
  • Crushing, dissolving, or breaking pills can lead to immediate overdose, which can cause severe side effects or even fatal outcomes.
  • If you are planning to buy Tapentadol immediate release pills online, it is best to purchase contraceptive pills or condoms too. Prolonged use of this medicine during pregnancy can lead to an adverse effect on fetal development.
  • Consuming alcohol, along with Tapentadol, can lead to a fatal outcome.
  • Using CNS (central nervous system) depressant with Tapentadol IR can lead to respiratory depression, sedation, coma, or even death.
  • Using serotonin antidepressants and Tapentadol can lead to serotonin syndrome, which can cause fever, muscle rigidity, seizure, and even death.

Schedule II drug

Tapentadol IR is a schedule II drug, a controlled substance. FDA has classifications for pills from Schedule I to V. Schedule I pills have a very high probability of causing dependency, whereas Schedule V does not induce habit-formation. Most of the countries consider Schedule I and II drugs as controlled substances. Thus, if you are flying with Tapentadol IR pills, carry only the prescribed amount and the doctor’s prescription.

Why choose local online pharmacies?

While buying Tapentadol IR via online pharmacies, remember to choose local sites, especially when purchasing generic medicines. The rules and regulations for manufacturing pills, transportation, and testing are quite liberal in numerous countries. Thus, it is best to choose the local sites. Moreover, choose sites with a good reputation, excellent customer support, COD option, and an onsite pharmacist. Why is COD safe? COD or cash on delivery is a payment method in which the customer can wait for the package to reach them and then pay for the pills. If you choose a new site, or if you do not want to share personal bank details with a website, it is best to choose the COD option.


How to use Tapentadol IR?

Tapentadol IR is an oral pill. It is ideal to consume it orally with the required amount of water. If you have nausea or stomach upset, it is best to consume it after food. If nausea persists, lay down for an hour after consuming the pill. It will ease the side effect. Consume the medicine when you experience the first pain symptom. Do not wait for the pain to worsen beyond control. The pill takes an average of 30-50 minutes (maximum one hour) to work. So, do not overdose for immediate effect. Do not consume it for a prolonged period beyond recommended in the prescription.

When you stop the drug, you might experience withdrawal effects. Withdrawal symptoms can be as simple as restlessness, insomnia, watery eyes, muscle ache, diarrhea, or sweating. In some cases, the withdrawal symptom can be severe, like hallucination, suicidal thoughts, change in behavior, anxiety, and others. Thus, talk to your doctor about a tapering dose to deal with withdrawal symptoms. Some tend to consume more pills to avoid withdrawal symptoms, which is a sure way to get addicted to Tapentadol.


How to store the pill?

Keep it in the package, until needed. Keep it away from moisture, as moisture can damage the covering film of the pill. The pill can cause an adverse effect on children. Thus, keep it away from pets and children. Remember that Tapentadol prescribed for one medical condition or type of pain is not the right medicine or dose for another pain. For instance, if the pill was for post-surgery pain management, do not use the same dose and pill for muscle pain or others. The dosage and course of treatment vary with the severity of pain, chronic/acute pain, and so on.


The best way to order Tapentadol is after getting a doctor’s prescription. Talk to your doctor about your medical history and the severity of the pain. Some people might be allergic to Tapentadol. If you had allergic reactions to any pain killers in the past, share the medical information with him. After receiving the prescription, choose a reliable online pharmacy and buy the same brand/generic and same dose levels. It is best to use the same dose, as recommended. Do not purchase 100mg pills and break it into two for 50mg dose. In the same way, using two 50mg tablets for 100mg dosage can also cause adverse effects in certain situations.